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Absence of Interleukin-4 Determines Less Severe Pulmonary Paracoccidioidomycosis Associated with Impaired Th2 Response

Host resistance to paracoccidiodomycosis, the main deep mycosis in Latin America, is mainly due to cellular immunity and gamma interferon (IFN-γ) production. To assess the role of interleukin-4 (IL-4), a Th2-inducing cytokine, pulmonary paracoccidioidomycosis was studied in IL-4-deficient (IL-4(−/−)...

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Hlavní autoři: Pina, Adriana, Valente-Ferreira, Rita C., Molinari-Madlum, Eugênia E. W., Vaz, Celidéia A. C., Keller, Alexandre C., Calich, Vera L. G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC375147/
https://ncbi.nlm.nih.gov/pubmed/15039362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.4.2369-2378.2004
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