Effects of lovastatin treatment on the metabolic distributions in the Han:SPRD rat model of polycystic kidney disease

BACKGROUND: We previously demonstrated that lovastatin decreases cyst volume and improves kidney function in the Han:SPRD (Cy/+) rat model of ADPKD. Since endothelial dysfunction and inflammatory activity are evident in patients with ADPKD, we investigated whether lovastatin reduces the inflammation...

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Main Authors: Klawitter, Jelena, Zafar, Iram, Klawitter, Jost, Pennington, Alexander T, Klepacki, Jacek, Gitomer, Berenice Y, Schrier, Robert W, Christians, Uwe, Edelstein, Charles L
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751441/
https://ncbi.nlm.nih.gov/pubmed/23902712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-14-165
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