The Sex Chromosome Trisomy mouse model of XXY and XYY: metabolism and motor performance

BACKGROUND: Klinefelter syndrome (KS), caused by XXY karyotype, is characterized by low testosterone, infertility, cognitive deficits, and increased prevalence of health problems including obesity and diabetes. It has been difficult to separate direct genetic effects from hormonal effects in human s...

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Main Authors: Chen, Xuqi, Williams-Burris, Shayna M, McClusky, Rebecca, Ngun, Tuck C, Ghahramani, Negar, Barseghyan, Hayk, Reue, Karen, Vilain, Eric, Arnold, Arthur P
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751353/
https://ncbi.nlm.nih.gov/pubmed/23926958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2042-6410-4-15
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