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The Number of X Chromosomes Causes Sex Differences in Adiposity in Mice

Sexual dimorphism in body weight, fat distribution, and metabolic disease has been attributed largely to differential effects of male and female gonadal hormones. Here, we report that the number of X chromosomes within cells also contributes to these sex differences. We employed a unique mouse model...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Chen, Xuqi, McClusky, Rebecca, Chen, Jenny, Beaven, Simon W., Tontonoz, Peter, Arnold, Arthur P., Reue, Karen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349739/
https://ncbi.nlm.nih.gov/pubmed/22589744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002709
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