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The Number of X Chromosomes Causes Sex Differences in Adiposity in Mice
Sexual dimorphism in body weight, fat distribution, and metabolic disease has been attributed largely to differential effects of male and female gonadal hormones. Here, we report that the number of X chromosomes within cells also contributes to these sex differences. We employed a unique mouse model...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3349739/ https://ncbi.nlm.nih.gov/pubmed/22589744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002709 |
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