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TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors

To achieve an efficient intracellular drug and DNA delivery, attempts were made to target microparticulate drug carriers into cytoplasm bypassing the endocytotic pathway. TAT peptides derived from the HIV-1 TAT protein facilitate intracellular delivery of proteins and small colloidal particles. We d...

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Bibliografiske detaljer
Main Authors: Torchilin, Vladimir P., Rammohan, Ram, Weissig, Volkmar, Levchenko, Tatyana S.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC37513/
https://ncbi.nlm.nih.gov/pubmed/11438707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.151247498
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