The antimicrobial lysine-peptoid hybrid LP5 inhibits DNA replication and induces the SOS response in Staphylococcus aureus

BACKGROUND: The increase in antibiotic resistant bacteria has led to renewed interest in development of alternative antimicrobial compounds such as antimicrobial peptides (AMPs), either naturally-occurring or synthetically-derived. Knowledge of the mode of action (MOA) of synthetic compounds mimicki...

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Hlavní autoři: Gottschalk, Sanne, Ifrah, Dan, Lerche, Sandra, Gottlieb, Caroline T, Cohn, Marianne T, Hiasa, Hiroshi, Hansen, Paul R, Gram, Lone, Ingmer, Hanne, Thomsen, Line E
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751284/
https://ncbi.nlm.nih.gov/pubmed/23945181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-13-192
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