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Isolation of midgut escape mutants of two American genotype dengue 2 viruses from Aedes aegypti

BACKGROUND: Several studies have shown that American genotype dengue 2 viruses (DENV2) have reduced viral fitness in the mosquito vector, Aedes aegypti, compared to other DENV2 genotypes. Diminished replication efficiency or inability to efficiently traverse membrane barriers encompassing organs suc...

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Autori principali: Khoo, Cynthia CH, Doty, Jeffrey B, Held, Nicole L, Olson, Ken E, Franz, Alexander WE
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751248/
https://ncbi.nlm.nih.gov/pubmed/23937713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-10-257
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