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Cell-cycle synchronization reverses Taxol resistance of human ovarian cancer cell lines
BACKGROUND: Taxol is a powerful chemotherapy agent leading to mitotic arrest and cell death; however, its clinical efficacy has been hampered due to the development of drug resistance. Taxol specifically targets the cell cycle. Progress through mitosis (M stage) is an absolute requirement for drug-i...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3751242/ https://ncbi.nlm.nih.gov/pubmed/23899403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-13-77 |
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