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Induction of apoptosis by taxol and cisplatin and effect on cell cycle-related proteins in cisplatin-sensitive and -resistant human ovarian cells.

The effect of taxol (TX) and cisplatin (CDDP), singly or in association, was assessed on two human ovarian cancer cell lines, one sensitive (A2780) and one resistant (A2780 cp8) to CDDP. Cell lines showed a similar sensitivity to TX, whereas different cytotoxicity results were obtained in the two ce...

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Detalhes bibliográficos
Main Authors: Zaffaroni, N., Silvestrini, R., Orlandi, L., Bearzatto, A., Gornati, D., Villa, R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150188/
https://ncbi.nlm.nih.gov/pubmed/9652752
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