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Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice
We previously reported the disruption of the murine gene encoding the transcription factor USF2 and its consequences on glucose-dependent gene regulation in the liver. We report here a peculiar phenotype of Usf2(−/−) mice that progressively develop multivisceral iron overload; plasma iron overcomes...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The National Academy of Sciences
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC37512/ https://ncbi.nlm.nih.gov/pubmed/11447267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.151179498 |
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