Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice

We previously reported the disruption of the murine gene encoding the transcription factor USF2 and its consequences on glucose-dependent gene regulation in the liver. We report here a peculiar phenotype of Usf2(−/−) mice that progressively develop multivisceral iron overload; plasma iron overcomes...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Nicolas, Gaël, Bennoun, Myriam, Devaux, Isabelle, Beaumont, Carole, Grandchamp, Bernard, Kahn, Axel, Vaulont, Sophie
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 2001
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC37512/
https://ncbi.nlm.nih.gov/pubmed/11447267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.151179498
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