Activation of NF-κB by nontypeable Hemophilus influenzae is mediated by toll-like receptor 2-TAK1-dependent NIK–IKKα/β–IκBα and MKK3/6–p38 MAP kinase signaling pathways in epithelial cells

Nontypeable Hemophilus influenzae (NTHi) is an important human pathogen in both children and adults. In children, it causes otitis media, the most common childhood infection and the leading cause of conductive hearing loss in the United States. In adults, it causes lower respiratory tract infections...

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Hlavní autoři: Shuto, Tsuyoshi, Xu, Haidong, Wang, Beinan, Han, Jiahuai, Kai, Hirofumi, Gu, Xin-Xing, Murphy, Timothy F., Lim, David J., Li, Jian-Dong
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2001
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC37511/
https://ncbi.nlm.nih.gov/pubmed/11438700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.151236098
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