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Activation of NF-κB by nontypeable Hemophilus influenzae is mediated by toll-like receptor 2-TAK1-dependent NIK–IKKα/β–IκBα and MKK3/6–p38 MAP kinase signaling pathways in epithelial cells

Nontypeable Hemophilus influenzae (NTHi) is an important human pathogen in both children and adults. In children, it causes otitis media, the most common childhood infection and the leading cause of conductive hearing loss in the United States. In adults, it causes lower respiratory tract infections...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Shuto, Tsuyoshi, Xu, Haidong, Wang, Beinan, Han, Jiahuai, Kai, Hirofumi, Gu, Xin-Xing, Murphy, Timothy F., Lim, David J., Li, Jian-Dong
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2001
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC37511/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11438700/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.151236098
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