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Rac1 Regulates the Activity of mTORC1 and mTORC2 and Controls Cellular Size

Mammalian target of rapamycin (mTOR) is a serine/threonine kinase that exists in two separate complexes, mTORC1 and mTORC2, that function to control cell size and growth in response to growth factors, nutrients, and cellular energy levels. Low molecular weight GTP-binding proteins of the Rheb and Ra...

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Autors principals: Saci, Abdelhafid, Cantley, Lewis C., Carpenter, Christopher L.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750737/
https://ncbi.nlm.nih.gov/pubmed/21474067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.03.017
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