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Rac1 Regulates the Activity of mTORC1 and mTORC2 and Controls Cellular Size

Mammalian target of rapamycin (mTOR) is a serine/threonine kinase that exists in two separate complexes, mTORC1 and mTORC2, that function to control cell size and growth in response to growth factors, nutrients, and cellular energy levels. Low molecular weight GTP-binding proteins of the Rheb and Ra...

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Hlavní autoři: Saci, Abdelhafid, Cantley, Lewis C., Carpenter, Christopher L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750737/
https://ncbi.nlm.nih.gov/pubmed/21474067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.03.017
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