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Nuclear reprogramming with c-Myc potentiates glycolytic capacity of derived induced pluripotent stem cells

Reprogramming strategies influence the differentiation capacity of derived induced pluripotent stem (iPS) cells. Removal of the reprogramming factor c-Myc reduces tumorigenic incidence and increases cardiogenic potential of iPS cells. c-Myc is a regulator of energy metabolism, yet the impact on meta...

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Detalhes bibliográficos
Main Authors: Folmes, Clifford D. L., Martinez-Fernandez, Almudena, Faustino, Randolph S., Yamada, Satsuki, Perez-Terzic, Carmen, Nelson, Timothy J., Terzic, Andre
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750736/
https://ncbi.nlm.nih.gov/pubmed/23247633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12265-012-9431-2
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