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Preparation and Evaluation at the Delta Opioid Receptor of a Series of Linear Leu-Enkephalin Analogues Obtained by Systematic Replacement of the Amides

[Image: see text] Leu-enkephalin analogues, in which the amide bonds were sequentially and systematically replaced either by ester or N-methyl amide bonds, were prepared using classical organic chemistry as well as solid phase peptide synthesis (SPPS). The peptidomimetics were characterized using co...

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Detalhes bibliográficos
Main Authors: Rochon, Kristina, Proteau-Gagné, Arnaud, Bourassa, Philippe, Nadon, Jean-François, Côté, Jérome, Bournival, Véronique, Gobeil, Fernand, Guérin, Brigitte, Dory, Yves L., Gendron, Louis
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750687/
https://ncbi.nlm.nih.gov/pubmed/23650868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn4000583
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