Mitochondria-targeted antioxidant MitoQ ameliorates experimental mouse colitis by suppressing NLRP3 inflammasome-mediated inflammatory cytokines

BACKGROUND: MitoQ is a mitochondria-targeted derivative of the antioxidant ubiquinone, with antioxidant and anti-apoptotic functions. Reactive oxygen species are involved in many inflammatory diseases including inflammatory bowel disease. In this study, we assessed the therapeutic effects of MitoQ i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dashdorj, Amarjargal, KR, Jyothi, Lim, Sangbin, Jo, Ara, Nguyen, Minh Nam, Ha, Joohun, Yoon, Kyung-Sik, Kim, Hyo Jong, Park, Jae-Hoon, Murphy, Michael P, Kim, Sung Soo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2013
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750576/
https://ncbi.nlm.nih.gov/pubmed/23915129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7015-11-178
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