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Late developing mammary tumors and hyperplasia induced by a low-oncogenic variant of mouse mammary tumor virus (MMTV) express genes identical to those induced by canonical MMTV

BACKGROUND: The canonical milk-transmitted mouse mammary tumor virus (MMTV) of C3H mice (C3H-MMTV) rapidly induces tumors in 90% of infected animals by 8 months of age. Pro-viral insertions of C3H-MMTV into genomic DNA results in the overexpression of common core insertion site (CIS) genes, includin...

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Detalhes bibliográficos
Main Authors: Bruno, Robert D, Rosenfield, Sonia M, Smith, Gilbert H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750450/
https://ncbi.nlm.nih.gov/pubmed/23866257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-79
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