Partial ADAMTS13 deficiency in atypical hemolytic uremic syndrome

Complement dysregulation leads to atypical hemolytic uremic syndrome (aHUS), while ADAMTS13 deficiency causes thrombotic thrombocytopenic purpura. We investigated whether genetic variations in the ADAMTS13 gene partially explain the reduced activity known to occur in some patients with aHUS. We meas...

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Detalhes bibliográficos
Main Authors: Feng, Shuju, Eyler, Stephen J., Zhang, Yuzhou, Maga, Tara, Nester, Carla M., Kroll, Michael H., Smith, Richard J., Afshar-Kharghan, Vahid
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750341/
https://ncbi.nlm.nih.gov/pubmed/23847193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-03-492421
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