Partial ADAMTS13 deficiency in atypical hemolytic uremic syndrome

Complement dysregulation leads to atypical hemolytic uremic syndrome (aHUS), while ADAMTS13 deficiency causes thrombotic thrombocytopenic purpura. We investigated whether genetic variations in the ADAMTS13 gene partially explain the reduced activity known to occur in some patients with aHUS. We meas...

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Autori principali: Feng, Shuju, Eyler, Stephen J., Zhang, Yuzhou, Maga, Tara, Nester, Carla M., Kroll, Michael H., Smith, Richard J., Afshar-Kharghan, Vahid
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2013
Soggetti:
Thrombosis and Hemostasis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750341/
https://ncbi.nlm.nih.gov/pubmed/23847193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-03-492421
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