Partial ADAMTS13 deficiency in atypical hemolytic uremic syndrome

Complement dysregulation leads to atypical hemolytic uremic syndrome (aHUS), while ADAMTS13 deficiency causes thrombotic thrombocytopenic purpura. We investigated whether genetic variations in the ADAMTS13 gene partially explain the reduced activity known to occur in some patients with aHUS. We meas...

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Autors principals: Feng, Shuju, Eyler, Stephen J., Zhang, Yuzhou, Maga, Tara, Nester, Carla M., Kroll, Michael H., Smith, Richard J., Afshar-Kharghan, Vahid
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2013
Matèries:
Thrombosis and Hemostasis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750341/
https://ncbi.nlm.nih.gov/pubmed/23847193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-03-492421
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