Serine protease inhibitor-6 plays a critical role in protecting murine Granzyme B-producing regulatory T-cells

Regulatory T-cells (Tregs) play a pivotal role in the maintenance of immune tolerance and hold great promise as cell therapy for a variety of immune-mediated diseases. However, the cellular mechanisms that regulate Treg maintenance and homeostasis have yet to be fully explored. While Tregs express G...

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Autori principali: Azzi, Jamil, Skartsis, Nikolaos, Mounayar, Marwan, Magee, Ciara N., Batal, Ibrahim, Ting, Christopher, Moore, Robert, Riella, Leonardo V., Ohori, Shunsuke, Abdoli, Rozita, Smith, Brian, Fiorina, Paolo, Heathcote, Dean, Bakhos, Tannous, Ashton-Rickardt, Philip G., Abdi, Reza
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750098/
https://ncbi.nlm.nih.gov/pubmed/23913965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300851
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