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ACK1 Tyrosine Kinase: Targeted Inhibition to Block Cancer Cell Proliferation
ACK1 tyrosine kinase, located on chromosome 3q29, is aberrantly activated, amplified or mutated in a wide variety of human cancers. While the deregulated kinase is oncogenic and its activation correlates with progression to metastatic stage, its inhibition causes cell cycle arrest, sensitizes cells...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3750075/ https://ncbi.nlm.nih.gov/pubmed/23597703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2013.04.004 |
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