Polymorphisms of the Tissue Inhibitor of Metalloproteinase 3 Gene Are Associated with Resistance to High-Altitude Pulmonary Edema (HAPE) in a Japanese Population: A Case Control Study Using Polymorphic Microsatellite Markers

INTRODUCTION: High-altitude pulmonary edema (HAPE) is a hypoxia-induced, life-threatening, high permeability type of edema attributable to pulmonary capillary stress failure. Genome-wide association analysis is necessary to better understand how genetics influence the outcome of HAPE. MATERIALS AND...

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Hauptverfasser: Kobayashi, Nobumitsu, Hanaoka, Masayuki, Droma, Yunden, Ito, Michiko, Katsuyama, Yoshihiko, Kubo, Keishi, Ota, Masao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750038/
https://ncbi.nlm.nih.gov/pubmed/23991023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071993
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