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The association of Toll-like receptor 4 gene polymorphisms with the development of emphysema in Japanese subjects: a case control study
BACKGROUND: The principal role of Toll-like receptor 4 (TLR4) is the induction of immune responses to lipopolysaccharides. Previously, mice deficient in the TLR4 gene exhibited up-regulation of the NADPH oxidase system in the lungs. This resulted in increased oxidant generation and elastolytic activ...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3333474/ https://ncbi.nlm.nih.gov/pubmed/22251849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-5-36 |
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