Phosphorylation of Calcineurin at a Novel Serine-Proline Rich Region Orchestrates Hyphal Growth and Virulence in Aspergillus fumigatus

The fungus Aspergillus fumigatus is a leading infectious killer in immunocompromised patients. Calcineurin, a calmodulin (CaM)-dependent protein phosphatase comprised of calcineurin A (CnaA) and calcineurin B (CnaB) subunits, localizes at the hyphal tips and septa to direct A. fumigatus invasion and...

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Detalhes bibliográficos
Main Authors: Juvvadi, Praveen R., Gehrke, Christopher, Fortwendel, Jarrod R., Lamoth, Frédéric, Soderblom, Erik J., Cook, Erik C., Hast, Michael A., Asfaw, Yohannes G., Moseley, M. Arthur, Creamer, Trevor P., Steinbach, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749960/
https://ncbi.nlm.nih.gov/pubmed/23990785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003564
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