Multiple Pathways Promote Dynamical Coupling between Catalytic Domains in Escherichia coli Prolyl-tRNA Synthetase

Aminoacyl-tRNA synthetases are multi-domain enzymes that catalyze covalent attachment of amino acids to their cognate tRNA. Cross-talk between functional domains is a prerequisite for this process. In the present study, we investigate the molecular mechanism of site-to-site communication in Escheric...

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Main Authors: Johnson, James M., Sanford, Brianne L., Strom, Alexander M., Tadayon, Stephanie N., Lehman, Brent P., Zirbes, Arrianna M., Bhattacharyya, Sudeep, Musier-Forsyth, Karin, Hati, Sanchita
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749879/
https://ncbi.nlm.nih.gov/pubmed/23731272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400079h
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