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Dual AAV therapy ameliorates exercise-induced muscle injury and functional ischemia in murine models of Duchenne muscular dystrophy

Neuronal nitric oxide synthase (nNOS) membrane delocalization contributes to the pathogenesis of Duchenne muscular dystrophy (DMD) by promoting functional muscle ischemia and exacerbating muscle injury during exercise. We have previously shown that supra-physiological expression of nNOS-binding mini...

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Bibliographic Details
Main Authors: Zhang, Yadong, Yue, Yongping, Li, Liang, Hakim, Chady H., Zhang, Keqing, Thomas, Gail D., Duan, Dongsheng
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749861/
https://ncbi.nlm.nih.gov/pubmed/23681067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt224
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