Somatic mosaicism in Wiskott–Aldrich syndrome suggests in vivo reversion by a DNA slippage mechanism

Somatic mosaicism caused by in vivo reversion of inherited mutations has been described in several human genetic disorders. Back mutations resulting in restoration of wild-type sequences and second-site mutations leading to compensatory changes have been shown in mosaic individuals. In most cases, h...

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出版年:	Proc Natl Acad Sci U S A
主要な著者:	Wada, Taizo, Schurman, Shepherd H., Otsu, Makoto, Garabedian, Elizabeth K., Ochs, Hans D., Nelson, David L., Candotti, Fabio
フォーマット:	Artigo
言語:	Inglês
出版事項:	National Academy of Sciences 2001
主題:	Biological Sciences
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC37498/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11447283/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.151260498
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