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Inhibition of Cisplatin-Induced Lipid Catabolism and Weight Loss by Ghrelin in Male Mice

Cachexia, defined as an involuntary weight loss ≥5%, is a serious and dose-limiting side effect of chemotherapy that decreases survival in cancer patients. Alterations in lipid metabolism are thought to cause the lipodystrophy commonly associated with cachexia. Ghrelin has been proposed to ameliorat...

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Main Authors: Garcia, Jose M., Scherer, Thomas, Chen, Ji-an, Guillory, Bobby, Nassif, Anriada, Papusha, Victor, Smiechowska, Joanna, Asnicar, Mark, Buettner, Christoph, Smith, Roy G.
格式: Artigo
語言:Inglês
出版: Endocrine Society 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749475/
https://ncbi.nlm.nih.gov/pubmed/23832960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-1179
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