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Mesenchymal Stem Cell Durotaxis Depends on Substrate Stiffness Gradient Strength

Mesenchymal stem cells (MSCs) respond to niche elasticity, which varies between and within tissues. Stiffness gradients result from pathological conditions but also occur through normal variation, e.g. muscle. MSCs undergo directed migration even in response to shallow stiffness gradients before dif...

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Detalhes bibliográficos
Main Authors: Vincent, Ludovic G., Choi, Yu Suk, Alonso-Latorre, Baldomero, del Álamo, Juan C., Engler, Adam J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749305/
https://ncbi.nlm.nih.gov/pubmed/23390141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/biot.201200205
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