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Intrinsic Noise of microRNA-Regulated Genes and the ceRNA Hypothesis

MicroRNAs are small noncoding RNAs that regulate genes post-transciptionally by binding and degrading target eukaryotic mRNAs. We use a quantitative model to study gene regulation by inhibitory microRNAs and compare it to gene regulation by prokaryotic small non-coding RNAs (sRNAs). Our model uses a...

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Détails bibliographiques
Auteurs principaux: Noorbakhsh, Javad, Lang, Alex H., Mehta, Pankaj
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749174/
https://ncbi.nlm.nih.gov/pubmed/23991139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072676
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