Mnt1p and Mnt2p of Candida albicans Are Partially Redundant α-1,2-Mannosyltransferases That Participate in O-Linked Mannosylation and Are Required for Adhesion and Virulence

The MNT1 gene of the human fungal pathogen Candida albicans is involved in O-glycosylation of cell wall and secreted proteins and is important for adherence of C. albicans to host surfaces and for virulence. Here we describe the molecular analysis of CaMNT2, a second member of the MNT1-like gene fam...

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Autores principales: Munro, Carol A., Bates, Steven, Buurman, Ed T., Hughes, H. Bleddyn, MacCallum, Donna M., Bertram, Gwyneth, Atrih, Abdel, Ferguson, Michael A. J., Bain, Judith M., Brand, Alexandra, Hamilton, Suzanne, Westwater, Caroline, Thomson, Lynn M., Brown, Alistair J. P., Odds, Frank C., Gow, Neil A. R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2004
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749086/
https://ncbi.nlm.nih.gov/pubmed/15519997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M411413200
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