Platelet Activation and Platelet-Monocyte Aggregate Formation Contribute to Decreased Platelet Count During Acute Simian Immunodeficiency Virus Infection in Pig-tailed Macaques

Platelets are key participants in innate immune responses to pathogens. As a decrease in circulating platelet count is one of the initial hematologic indicators of human immunodeficiency virus (HIV) infection, we sought to determine whether decline in platelet number during acute infection results f...

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Hauptverfasser: Metcalf Pate, Kelly A., Lyons, Claire E., Dorsey, Jamie L., Shirk, Erin N., Queen, Suzanne E., Adams, Robert J., Gama, Lucio, Morrell, Craig N., Mankowski, Joseph L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
Schlagworte:
Major Articles and Brief Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749014/
https://ncbi.nlm.nih.gov/pubmed/23852120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit278
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