Platelet Activation and Platelet-Monocyte Aggregate Formation Contribute to Decreased Platelet Count During Acute Simian Immunodeficiency Virus Infection in Pig-tailed Macaques

Platelets are key participants in innate immune responses to pathogens. As a decrease in circulating platelet count is one of the initial hematologic indicators of human immunodeficiency virus (HIV) infection, we sought to determine whether decline in platelet number during acute infection results f...

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Библиографические подробности
Главные авторы: Metcalf Pate, Kelly A., Lyons, Claire E., Dorsey, Jamie L., Shirk, Erin N., Queen, Suzanne E., Adams, Robert J., Gama, Lucio, Morrell, Craig N., Mankowski, Joseph L.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2013
Предметы:
Major Articles and Brief Reports
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749014/
https://ncbi.nlm.nih.gov/pubmed/23852120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit278
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