Platelet Activation and Platelet-Monocyte Aggregate Formation Contribute to Decreased Platelet Count During Acute Simian Immunodeficiency Virus Infection in Pig-tailed Macaques

Platelets are key participants in innate immune responses to pathogens. As a decrease in circulating platelet count is one of the initial hematologic indicators of human immunodeficiency virus (HIV) infection, we sought to determine whether decline in platelet number during acute infection results f...

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Bibliografiske detaljer
Main Authors: Metcalf Pate, Kelly A., Lyons, Claire E., Dorsey, Jamie L., Shirk, Erin N., Queen, Suzanne E., Adams, Robert J., Gama, Lucio, Morrell, Craig N., Mankowski, Joseph L.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Major Articles and Brief Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749014/
https://ncbi.nlm.nih.gov/pubmed/23852120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit278
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