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Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development
Runx (Cbfa/AML) transcription factors are critical for tissue-specific gene expression. A unique targeting signal in the C terminus directs Runx factors to discrete foci within the nucleus. Using Runx2/CBFA1/AML3 and its essential role in osteogenesis as a model, we investigated the fundamental impo...
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Główni autorzy: | , , , , , , , , , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
The National Academy of Sciences
2001
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC37490/ https://ncbi.nlm.nih.gov/pubmed/11438701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.151236498 |
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