A Novel Low-Molecular-Weight Compound Enhances Ectopic Bone Formation and Fracture Repair

BACKGROUND: Use of recombinant human bone morphogenetic protein-2 (rhBMP-2) is expensive and may cause local side effects. A small synthetic molecule, SVAK-12, has recently been shown in vitro to potentiate rhBMP-2-induced transdifferentiation of myoblasts into the osteoblastic phenotype. The aims o...

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Bibliographische Detailangaben
Hauptverfasser: Wong, Eugene, Sangadala, Sreedhara, Boden, Scott D., Yoshioka, Katsuhito, Hutton, William C., Oliver, Colleen, Titus, Louisa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Journal of Bone and Joint Surgery, Inc. 2013
Schlagworte:
Scientific Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748970/
https://ncbi.nlm.nih.gov/pubmed/23467869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2106/JBJS.L.00275
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