Preparation and characterization of monomethoxy poly(ethylene glycol)-poly(ε-caprolactone) micelles for the solubilization and in vivo delivery of luteolin

Luteolin (Lu) is one of the flavonoids with anticancer activity, but its poor water solubility limits its use clinically. In this work, we used monomethoxy poly(ethylene glycol)-poly(e-caprolactone) (MPEG-PCL) micelles to encapsulate Lu by a self-assembly method, creating a water-soluble Lu/MPEG-PCL...

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Bibliographische Detailangaben
Hauptverfasser: Qiu, Jin-Feng, Gao, Xiang, Wang, Bi-Lan, Wei, Xia-Wei, Gou, Ma-Ling, Men, Ke, Liu, Xing-Yu, Guo, Gang, Qian, Zhi-Yong, Huang, Mei-Juan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2013
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748903/
https://ncbi.nlm.nih.gov/pubmed/23990719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S45062
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