Preparation and characterization of monomethoxy poly(ethylene glycol)-poly(ε-caprolactone) micelles for the solubilization and in vivo delivery of luteolin

Luteolin (Lu) is one of the flavonoids with anticancer activity, but its poor water solubility limits its use clinically. In this work, we used monomethoxy poly(ethylene glycol)-poly(e-caprolactone) (MPEG-PCL) micelles to encapsulate Lu by a self-assembly method, creating a water-soluble Lu/MPEG-PCL...

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Hlavní autoři: Qiu, Jin-Feng, Gao, Xiang, Wang, Bi-Lan, Wei, Xia-Wei, Gou, Ma-Ling, Men, Ke, Liu, Xing-Yu, Guo, Gang, Qian, Zhi-Yong, Huang, Mei-Juan
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2013
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748903/
https://ncbi.nlm.nih.gov/pubmed/23990719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S45062
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