Preparation and characterization of monomethoxy poly(ethylene glycol)-poly(ε-caprolactone) micelles for the solubilization and in vivo delivery of luteolin

Luteolin (Lu) is one of the flavonoids with anticancer activity, but its poor water solubility limits its use clinically. In this work, we used monomethoxy poly(ethylene glycol)-poly(e-caprolactone) (MPEG-PCL) micelles to encapsulate Lu by a self-assembly method, creating a water-soluble Lu/MPEG-PCL...

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Detalhes bibliográficos
Main Authors: Qiu, Jin-Feng, Gao, Xiang, Wang, Bi-Lan, Wei, Xia-Wei, Gou, Ma-Ling, Men, Ke, Liu, Xing-Yu, Guo, Gang, Qian, Zhi-Yong, Huang, Mei-Juan
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748903/
https://ncbi.nlm.nih.gov/pubmed/23990719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S45062
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