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Macromolecular juggling by ubiquitylation enzymes

The posttranslational modification of target proteins with ubiquitin and ubiquitin-like proteins is accomplished by the sequential action of E1, E2, and E3 enzymes. Members of the E1 and E3 enzyme families can undergo particularly large conformational changes during their catalytic cycles, involving...

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Detalhes bibliográficos
Main Authors: Lorenz, Sonja, Cantor, Aaron J, Rape, Michael, Kuriyan, John
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748819/
https://ncbi.nlm.nih.gov/pubmed/23800009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-11-65
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