Differential Effect of Regional Drug Pressure on Dihydrofolate Reductase and Dihydropteroate Synthetase Mutations in Southern Mozambique

The prevalence and frequency of the dihydrofolate reductase (dhfr) and dihydropteroate synthetase (dhps) mutations associated with sulfadoxine–pyrimethamine (SP) resistance at 13 sentinel surveillance sites in southern Mozambique were examined regularly between 1999 and 2004. Frequency of the dhfr t...

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Hauptverfasser: Raman, Jaishree, Sharp, Brian, Kleinschmidt, Immo, Roper, Cally, Streat, Elizabeth, Kelly, Val, Barnes, Karen I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748784/
https://ncbi.nlm.nih.gov/pubmed/18256426
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