Suppression of Acute Graft-Versus-Host Response by TCDD Is Independent of the CTLA-4-IFN-γ-IDO pathway

Activation of the aryl hydrocarbon receptor (AhR) by its prototypic ligand, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), induces potent suppression of an acute graft-versus-host (GVH) response and prevents GVH disease (GVHD). Suppression is associated with development of a regulatory population of do...

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Detalhes bibliográficos
Main Authors: Rohlman, Diana, Punj, Sumit, Pennington, Jamie, Bradford, Sam, Kerkvliet, Nancy I.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748765/
https://ncbi.nlm.nih.gov/pubmed/23798565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kft140
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