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Telomerase expression and activity are coupled with myocyte proliferation and preservation of telomeric length in the failing heart

The role and even the existence of myocyte proliferation in the adult heart remain controversial. Documentation of cell cycle regulators, DNA synthesis, and mitotic images has not modified the view that myocardial growth can only occur from hypertrophy of an irreplaceable population of differentiate...

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Detalhes bibliográficos
Main Authors: Leri, Annarosa, Barlucchi, Laura, Limana, Federica, Deptala, Andrzej, Darzynkiewicz, Zbigniew, Hintze, Thomas H., Kajstura, Jan, Nadal-Ginard, Bernardo, Anversa, Piero
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC37486/
https://ncbi.nlm.nih.gov/pubmed/11447262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.151013298
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