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Role of T Cell Receptor Affinity in the Efficacy and Specificity of Adoptive T Cell Therapies

Over the last several years, there has been considerable progress in the treatment of cancer using gene modified adoptive T cell therapies. Two approaches have been used, one involving the introduction of a conventional αβ T cell receptor (TCR) against a pepMHC cancer antigen, and the second involvi...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Stone, Jennifer D., Kranz, David M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748443/
https://ncbi.nlm.nih.gov/pubmed/23970885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00244
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