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Enhanced Ca(2+)-dependent glutamate release from astrocytes of the BACHD Huntington’s disease mouse model

Huntington’s disease (HD) causes preferential loss of a subset of neurons in the brain although the huntingtin protein is expressed broadly in various neural cell types, including astrocytes. Glutamate-mediated excitotoxicity is thought to cause selective neuronal injury, and brain astrocytes have a...

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Bibliografische gegevens
Hoofdauteurs: Lee, William, Reyes, Reno C., Gottipati, Manoj K., Lewis, Karon, Lesort, Mathieu, Parpura, Vladimir, Gray, Michelle
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748209/
https://ncbi.nlm.nih.gov/pubmed/23756199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.06.002
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