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Plasmalemmal Na(+)/Ca(2+) exchanger modulates Ca(2+)-dependent exocytotic release of glutamate from rat cortical astrocytes

Astroglial excitability operates through increases in Ca(2+)(cyt) (cytosolic Ca(2+)), which can lead to glutamatergic gliotransmission. In parallel fluctuations in astrocytic Na(+)(cyt) (cytosolic Na(+)) control metabolic neuronal-glial signalling, most notably through stimulation of lactate product...

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Detalhes bibliográficos
Main Authors: Reyes, Reno C, Verkhratsky, Alexei, Parpura, Vladimir
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Neurochemistry 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3284767/
https://ncbi.nlm.nih.gov/pubmed/22268447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/AN20110059
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