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TFEB: Pathogenic role and therapeutic target in Parkinson disease
Parkinson disease (PD) is characterized by the progressive loss of nigral dopamine neurons and the presence of accumulations containing the disease-causing protein SNCA/α-synuclein. Here we review our recent findings describing how SNCA impairs the function of the master regulator of the autophagy-l...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Landes Bioscience
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3748195/ https://ncbi.nlm.nih.gov/pubmed/23715007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.25044 |
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