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TFEB: Pathogenic role and therapeutic target in Parkinson disease

Parkinson disease (PD) is characterized by the progressive loss of nigral dopamine neurons and the presence of accumulations containing the disease-causing protein SNCA/α-synuclein. Here we review our recent findings describing how SNCA impairs the function of the master regulator of the autophagy-l...

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Autors principals: Decressac, Mickael, Björklund, Anders
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748195/
https://ncbi.nlm.nih.gov/pubmed/23715007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.25044
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