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Elimination of Von Hippel-Lindau Function Perturbs Pancreas Endocrine Homeostasis in Mice
Mutations in the human homolog of the Vhlh gene [encoding the von-Hippel Lindau (VHL) protein] lead to tumor development. In mice, depletion of Vhlh in pancreatic ß-cells causes perturbed glucose homeostasis, but the role of this gene in other pancreatic cells is poorly understood. To investigate th...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3748057/ https://ncbi.nlm.nih.gov/pubmed/23977255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072213 |
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