Priming with Recombinant Auxotrophic BCG Expressing HIV-1 Gag, RT and Gp120 and Boosting with Recombinant MVA Induces a Robust T Cell Response in Mice

In previous studies we have shown that a pantothenate auxotroph of Myocbacterium bovis BCG (BCGΔpanCD) expressing HIV-1 subtype C Gag induced Gag-specific immune responses in mice and Chacma baboons after prime-boost immunization in combination with matched rMVA and VLP vaccines respectively. In thi...

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Hlavní autoři: Chapman, Rosamund, Stutz, Helen, Jacobs, William, Shephard, Enid, Williamson, Anna-Lise
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748047/
https://ncbi.nlm.nih.gov/pubmed/23977084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071601
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