Prevalence of PALB2 Mutations in Breast Cancer Patients in Multi-Ethnic Asian Population in Malaysia and Singapore

BACKGROUND: The partner and localizer of breast cancer 2 (PALB2) is responsible for facilitating BRCA2-mediated DNA repair by serving as a bridging molecule, acting as the physical and functional link between the breast cancer 1 (BRCA1) and breast cancer 2 (BRCA2) proteins. Truncating mutations in t...

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Main Authors: Phuah, Sze Yee, Lee, Sheau Yee, Kang, Peter, Kang, In Nee, Yoon, Sook-Yee, Thong, Meow Keong, Hartman, Mikael, Sng, Jen-Hwei, Yip, Cheng Har, Taib, Nur Aishah Mohd, Teo, Soo-Hwang
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748013/
https://ncbi.nlm.nih.gov/pubmed/23977390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073638
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